Chemoembolisation is a minimally invasive treatment performed by interventional radiologists to treat cancers (tumours) that have spread to the liver.
The main objective of the treatment is to deprive the tumour of the nourishment brought by the blood supply, by embolising its arteries (embolisation) and administering citostatics (anti-cancer drug) directly into the tumour.
In this way, the damage to healthy tissues is avoided and the tumour is starved by cut off the blood supply, which causes its shrinkage. Chemoembolisation is used for large tumours, particularly hepatocellular carcinoma (liver cancer), in cases when the tumour can not be treated by radiofrequency ablation (RFA), or as a combination with other cancer treatments (radiation therapy, RFA).
Using imaging for precise guidance, interventional radiologist threads the tiny catheter through the femoral artery (which is located in the groin) up to the artery that supplies liver tumour with the blood. When the desired location is reached the embolic agent and citostatic are injected through the catheter.
This procedure requires in hospital stay for a couple of days varying on the overall status of every individual patient.
Chemoembolisation is a palliative treatment and is effective for primary liver cancers particularly when combined with other treatments.
There are some promising results for treatment of metastatic tumours, but there is still more research to be conducted.
Author: Dr John Vrazas MB,BS FRANZCR